Smart and caring, CDC Doctor Abby Arcane's strong sense of empathy puts her at the center of a horrific life-threatening epidemic in her hometown, where she faces emotional demons from her past... while a chance meeting with scientist Alec Holland takes her into a world of horror and the supernatural, and of the elemental creature known as Swamp Thing.
Passionate biologist Alec Holland is caught in the crosshairs of a small town nightmare when he discovers a bizarre local illness may be connected to his work in the swamp. Holland's discovery leads him into conflict with dark forces, from which he emerges as the elemental hero known as Swamp Thing.
Emerging from the swamp with a monstrous physique and strange new powers over plant life, the man who was once Alec Holland struggles to hold onto his humanity. When dark forces converge on the town of Marais, Swamp Thing must embrace what he has become in order to defend the town as well as the natural world at large.
As its most prominent businessman, Avery Sunderland serves as the de facto patriarch of his Louisiana hometown, always giving back to the community. His benevolent veneer, however, masks a ruthless determination to harness the power of the swamp for profit.
Maria Sunderland traded in her privileged upbringing for the swamps of Marais when she married local business magnate Avery Sunderland, but Avery's life-time obsession with the swamp has driven a wedge between him and Maria. Her poised existence is shaken further when the return of Abby Arcane reawakens a deep grief over the loss of Maria's daughter, Shawna, drawing her into the dark supernatural mysteries emerging from the swamp.
Prickly genius Jason Woodrue is a biogeneticist without equal and he knows it. Brought in to study the unique properties of a small town Louisiana swamp, Woodrue becomes fixated on unlocking the potential contained within -- leading to tragic and monstrous consequences.
Son of town Sheriff Lucilia Cable, Matt Cable is also a member of the force, a lawman who would do anything for the town he cares about. But when his childhood crush, Abby Arcane, returns home just as an evil threatens the town he's sworn to protect, Matt is conflicted and driven to take desperate action.
Tough as nails and pragmatic, Sheriff Lucilia Cable's fierce devotion to her son, Matt, is rivaled only by her sworn duty to serve and protect the town of Marais. As the community she has dedicated her life to defending is beset by strange forces, Lucilia must double down in her efforts to safeguard everyone she holds dear.
Stuntman turned movie star, Daniel Cassidy became semi-famous after playing the demonic Blue Devil. But now, eight years later, Cassidy finds himself living out his days in frustration, pining for his former fame while on a collision course with destiny.
Liz Tremayne, a close childhood friend of Abby Arcane's, splits her time between reporting for the local paper and bartending at her aging father's roadhouse bar. Her no-nonsense attitude belies a deep compassion for her friends and family as she sets out in her uncompromising quest to expose the secrets that threaten her beloved hometown.
Madame Xanadu is a centuries-old sorceress who finds herself reluctantly drawn into battle against the escalating supernatural forces plaguing a small Louisiana town. A blind fortune teller and magical crusader, Xanadu's heart is in the right place despite her unorthodox methods in the fight against evil.